Health Conditions

The Effectiveness of CBD Oil for Epilepsy

CBD Oil for Epilepsy

Epilepsy is a common medical condition that normally affects the brain, leading to frequent seizures. The condition can start at any age and it has no cure. Even though there are clinical drugs that are used to reduce its symptoms, some people are now turning to alternative medications such as CBD. A high-quality CBD oil for epilepsy can help to significantly reduce epileptic episodes.

What is CBD?

Cannabidiol, also commonly known as CBD, is a chemical compound found in cannabis Sativa plants. It’s become prevalent in recent years due to its ability to treat a wide range of health complications. CBD can help to ease pain, inflammation and even treat seizures!

What Do Patients Need to Know About Using CBD as A Treatment Option

Epileptics need to know that CBD can play a significant role in easing the symptoms of their seizures. Preliminary studies plus user reviews show that the organic product is one of the most effective medicine sources. It’s not only ideal for reducing seizures but also improve overall wellness.

What is Epidiolex?

Epidiolex is the first FDA-approved cannabis-based medication to treat seizures caused by Dravet Syndrome, Lennox-Gastaut Syndrome, or tuberous sclerosis complex. According to reviews, Epidiolex provides a greater possibility of reducing seizures.

What Does FDA Approval of Epidiolex (CBD oral solution) Mean?

The FDA has approved epidiolex, a drug that contains a purified form of CBD. This means that patients can now get a clinical prescription for this oral solution as long as they are 1 year of age and older.

This means that the FDA has concluded that this drug is safe and effective for treating seizures. The FDA’s assurance and go-ahead indicate that the use of cannabis-derived treatments may also be approved for other types of treatments after a controlled study and review through the drug approval process.

Can It Work to Treat Certain Forms of Epilepsy?

CBD in the form of epidiolex can be used to treat certain forms of epilepsy. The most rigorous studies have been performed on people with these three forms of epilepsy:

Lennox-Gastaut Syndrome: it’s a condition that makes 2-5% of childhood epilepsy cases. Two 14-week clinical trials indicate that epidiolex can be useful in significantly reducing its symptoms.

Dravet syndrome: it’s a rare form of epilepsy that usually causes seizures. Dravet syndrome doesn’t respond well to prescription medications. However, a clinical trial done by a group of researchers showed a significant drop in the frequency of seizures in patients given epidiolex.

Note: these are the two types of seizures that have shown positive results after using epidiolex, a type of CBD-based drug. Both participants who were in the treatment group experienced an almost 40% decrease.

What the Evidence Shows?

Evidence suggests that epileptics who take CBD oil usually experience an almost 40% reduction in seizures. Medical cannabis may be useful since it contains anticonvulsant properties. Most research studies show that a combination of CBD with trace amounts of THC creates an organic with potent anticonvulsant properties.

Its effectiveness is based on its ability to interact with the biochemical found on the brain’s nerve cells. Even though CBD may reduce seizures in some types of epilepsy, the medical research related to it is still in its early stages.

What About Other Seizure Types?

CBD oil can also work to treat other types of seizures. A study was done on people with CDKL5 deficiency, a type of seizure where patients may experience multiple seizures per day and showed positive results.

The participants in this study had the symptoms, including the number and severity of the seizures being tracked after every two weeks. Throughout the 48-week study, the frequency of the seizures drops by more than 75%.

CBD Oil for Seizures in Adults & Children

Research done by GW Pharmaceuticals involving adults and children with Lennox-Gastaut/Dravet Syndrome produced results that finally led to FDA approval.

The participants were placed in two groups which included those in the placebo and those getting CBD. The results of those using CBD showed a positive improvement in the level of seizure symptoms.

A study published by the New England Journal of medicine in 2017, which included 120 children and young adults with epileptic conditions that were drug-resistant, also showed positive results. Some of the participants were placed on the placebo, which means they continued to use the standard anti-epileptic treatment.

The other participants were randomly assigned to 20 mg per kg of CBD of their body weight daily. The oral solution was given in two separate doses during a 14-week trial period.

On average, those who were placed on CBD treatment experienced a severe decrease in convulsive seizures. On average, the convulsive seizures reduced from around 13 seizures to about 6 seizures per month. This is almost more than a half.

Besides that, a minority of the patients became seizure-free, i.e., 5%. None in the placebo group was, however, able to become seizure-free.

From these studies, it’s clear that CBD significantly affects the frequency and severity of seizures. However, both adults and children have to be prepared to deal with unwanted side effects. There is also a need for extensive studies to establish how CBD acts and how it can be significantly minimized.

Note: when using CBD in children, caregivers need to be aware of this organic product’s long-term effectiveness and effects. A study done by the CNS drugs indicates that over four years, CBD was effective in around 27% of children with drug-resistant epilepsy. However, around 81% of the participants experienced mild side effects, while 23% experienced severe side effects.

CBD Oil for Dog Seizures

In a small study, scientists have established that 89% of dogs that received CBD oil in a clinical trial have a massive reduction in the frequency of their seizures. This simply means that CBD isn’t just ideal for treating epileptic seizures in human beings but also dogs.

Dogs enrolled in this trial were placed in the treatment and placebo groups. Those in the treatment group received CBD oil treatment for up to 12 weeks. The dogs in the placebo group were simply on the standard anticonvulsant drugs.

At the end of the trial, those dogs in the treatment group showed a significant reduction in the degree of seizures. This an exciting and promising finding. However, there is still the need for more research studies to fully determine the effectiveness of CBD oil for seizures in dogs.

CBD Oil Dosage for Seizures

If you are keen on using CBD oil for epilepsy, you need to understand how to use it and the dosage. It’s important to first engage your doctor and ask them how you should go about it. Currently, there is no universal guideline regarding the appropriate CBD oil dosage for seizures.

However, most manufacturers recommend that a person with seizures take a starting dose of epidiolex of 2.5 mg/kg twice daily. However, you can increase the dose gradually to 5 mg/kg daily after a week.

Suppose your individual tolerance and response are reasonable. In that case, you can still increase this amount until you reach 10 mg/kg twice per day.

It should be noted that your doctor will give you the best-customized dosage overview that suits your needs. Besides that, they will also help determine if the CBD will interact with any of the medications you are currently taking.

When taking CBD oil for seizures, always gradually increase your dosage. Besides that, you should reduce your dosage gradually if you want to stop. Don’t stop taking it abruptly because this may increase the level of seizure activity.

Stepwise Dosing Procedure

The aim should be to start low and go slow. With your doctor’s help, find the minimum effective CBD dosage and use it to establish the baseline. Maintain the baseline dosage for at least 7 days and take note of how it interacts with your body Increase the dosage gradually until you can experience the best results

Increase the daily dosage by 1-2 mg every 3 days until you establish a dosage that works for you. CBD Oil Dosing for Epilepsy and Seizures by Weight

Condition Range/Weight

  • 31-60 lbs.
  • 61-100 lbs.
  • 100-175 lbs.
  • 175-250 lbs.

Mild

  • 2 mg-4 mg+
  • 4 mg- 6mg+
  • 6 mg – 8 mg+
  • 8 mg- 10 mg+
  • 4 mg-8 mg+
  • 6 mg – 12 mg+
  • 8 mg- 18 mg+
  • 12 mg- 20 mg+

Medium

  • 8 mg-12 mg+
  • 12 mg – 18 mg+
  • 18 mg -24 mg+
  • 22 mg – 30 mg+
  • 12 mg-18 mg+
  • 18 mg – 24 mg+
  • 24 mg- 32 mg+
  • 32 mg- 40 mg+

Severe

  • 18 mg-30 mg+
  • 24 mg- 40 mg+
  • 32 mg-60 mg+
  • 42 mg-60 mg+

What Are the Potential Benefits & Risks?

CBD oil has a wide range of properties that make it ideal for treating several health complications. You can use it to treat physical health issues. Besides that, it’s ideal for managing mental ailments. Potential benefits of CBD oil include:

Reducing the Symptoms for Epilepsy

CBD oil for epilepsy has anti-seizure properties. It works with the endocannabinoid system to significantly reduce the frequency and severity of epileptic episodes. At the moment, there is epidiolex, a clinical drug that can be prescribed to epileptics.

Pain Relief

Many researchers have discovered that CBD has pain-relieving properties. By interacting with the endocannabinoid system. Doing so helps regulate the activities of neurotransmitters that bind to the pain receptors in the body.

In one laboratory study, it was established that CBD injections significantly reduced rats’ pain response to surgical incisions. Other related studies indicate that CBD treatment can also reduce sciatic nerve pain and inflammation.

Easing Anxiety and Depression

Anxiety and depression are currently the most common mental health issues. They have a significant health impact on the general wellbeing of the patient. According to the WHO, depression is currently the most significant contributor to disability worldwide.

While both anxiety and depression can be treated with pharmaceutical drugs, these drugs usually cause serious side effects. Besides that, they are costly and usually result in dependency.

On the other hand, CBD oil has shown a positive promise for its treatment. It’s a cost-effective natural approach that has anti-depressant and anti-anxiety properties.

Neuroprotective Properties

CBD’s ability to act on the endocannabinoid system and other brain signaling systems makes it ideal for those with neurological disorders. Epilepsy is one of the neurological disorders that this organic product helps to manage.

Apart from epidiolex for seizures, there is also Sativex, an oral spray that consists of CBD and THC. It has proven to be safe and effective in the management of neurological problems such as multiple sclerosis. This is because it works to reduce muscle spasticity by more than 50%.

But while CBD has profound potential health benefits, using it also comes with risks.

Risks of Using CBD Oil

Potential CBD oil side effects include:

  • Loss of appetite
  • Change in sleep patterns or sleepiness
  • Drowsiness
  • Dry mouth
  • Diarrhea
  • Increased thirst

Where to Find CBD Oil for Epilepsy & Seizures?

You can find CBD oil for epilepsy and seizures in some pharmacies. Besides that, numerous online stores sell CBD products. All you have to do is identify a reputable brand and choose a CBD oil product you can afford.

Generally, it’s good to buy CBD oil products direct from the manufacturer’s website. This way, you are guaranteed safe, high-quality, and effective CBD products.

Final Thought

CBD oil for epilepsy can be an effective remedy for those struggling with seizures. Epidiolex is the first FDA-approved drug that’s cannabis-based. It’s ideal for treating Dravet syndrome and Lennox-Gastaut syndrome, the two rare forms of epilepsy.

The organic product has proved to be effective in reducing the frequency and severity of the seizures. However, there is still a need for more research to fully establish CBD’s ability in treating epilepsy.

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